People with IDA have low blood levels of hemoglobin. Dizziness. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. You are encouraged to report side effects to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. Then the study was split into the following two groups, which are discussed below. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. (A generic drug is an exact copy of the active drug in a brand-name medication.) These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. endobj This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Procedure Details fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing And these two doses need to be separated by at least 7 days. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Phosphorus is an electrolyte that your body needs in order to make energy. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). Does Venofer Vial interact with other medications? To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. Follow your doctor's directions carefully. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. But if they become more severe or dont go away, talk with your doctor or pharmacist. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. A variety of tests can diagnose iron deficiency anemia. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. Following an LSD trip, users may experience a sort of 'comedown.'. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. Side effectswill last a very long time if the cause of them is not resolved. Hemoglobin is a protein thats found in your RBCs. So theres no recommended pediatric dosage for Injectafer. I hope you found answers and are feeling better now. If these effects continue or worsen, tell your doctor. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Call your doctor for medical advice about side effects. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. And this person had gotten their first dose of the drug without having an allergic reaction. What Is the Cost of Whole Genome Sequencing (WGS)? After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. But so far I feel better than before the infusion. (Hemoglobin is a protein thats found in red blood cells.). CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Below are examples of these side effects. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). However, since peoples bodies react so differently to drugs, they often have to change their stance on certain drugs. 4 0 obj Venofer is given as an infusion into a vein. Venofer is not for treating other forms of anemia not caused by iron deficiency. Call your doctor right away if you have serious side effects. The following information describes dosages that are commonly used or recommended. These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). This information is not specific medical advice and does not replace information you receive from the healthcare provider. Most of these side effects may go away within a few days or a couple of weeks. For instance, someone with lowblood pressuremay receive a medication to prevent migraines that lowersblood pressure, this may causeseriousside effects. Here we look at how Injectafer and Feraheme are alike and different. I got Venofer twice in the last few years and now my iron deficiency is worse than ever, first time my hemoglobin is down to 11,2. Understanding what thoseside effectsare can lead to a strategy to prevent them. Youll receive doses of either drug by a healthcare professional at a medical facility. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. Properly discard this product when it is expired or no longer needed. For people with certain medical implants, such as pacemakers, an MRI may pose an . Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Both Injectafer and Venofer belong to a class of medications called iron replacement products. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. As with all medications, the cost of Injectafer can vary. However, Injectafer has been studied for use in children with iron deficiency anemia (IDA). If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. Also tell them about any vitamins, herbs, and supplements you use. (A medication class describes a group of drugs that work in the same way.). Below are examples of these side effects. They can recommend if this is safe for you to do. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. These pregnancy-related problems include preterm delivery and low birth weight of your infant. Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. intense abdominal pain. Once inside your body, ferric carboxymaltose releases iron into your system. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. These nutrients include iron, vitamin B12, and folate. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Side effectsare uncomfortable reactions to medications or drugs. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Iron sucrose can also be mixed in a. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. administered at your doctors office or an infusion center. However, many people have no side effects or only have minor side effects. Always review your medical history with the treatingphysician. Your doctor will recommend whether you should stop taking your multivitamin or any other supplements. Keep in mind that there may be additional costs related to getting your doses of the drug at a medical facility. Follow all instructions closely. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. If you have questions about using Injectafer in a child, talk with your doctor. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. These tests will help make sure Injectafer is working to treat your iron deficiency anemia (IDA). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. fever. Learn about uses, cost, how it works, and more. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. <> Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . No, you wont need to take iron pills while youre using Injectafer. (See also Notes section.). In the second group, some people switched from taking iron by mouth to taking Injectafer. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. %PDF-1.3 Its not known if Injectafer is safe to take during pregnancy. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Vomiting. Do not start, stop, or change the dose of any drug without checking with your doctor. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Find out what health conditions may be a health risk when taken with Venofer Vial Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. (Hemoglobin is a protein thats found in your red blood cells.). Venofer is manufactured under license from Vifor (International) Inc., Switzerland. As a result, you may not make as much EPO as usual. There isnt a known interaction between Injectafer and alcohol. stream Theyll likely have you stop taking the pills while youre using Injectafer. <> FG Trade/E+ sia Getty Images Source: Wolters Kluwer Health. Here are answers to some frequently asked questions about Injectafer. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. Iron infusion benefits. You may need extra iron because of blood loss during kidney dialysis. Together, you and your doctor can develop a treatment plan thats best for you. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). You will be watched closely by your doctor for 30 minutes after each dose. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. Do not double the dose to catch up. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably.
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